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  • Writer's pictureMedlyfe Chemist

Alzheimer's Medicines and its effects

Alzheimer's is a progressive brain disorder that causes memory loss, reasoning, thinking and language skills, and perception difficulties. It is more common in older people, and the exact cause is not known but may include age-related changes, genetics, and lifestyle factors. While there is no cure for this disease, some medications can improve symptoms, and a healthy lifestyle and social engagement may delay onset. Symptoms typically start with memory loss and progress to include confusion, sleep disturbances, mood changes, speech problems, and difficulty with daily activities. Caregivers play a crucial role in providing support and assistance.


How do Alzheimer’s medicines work?


These medications work by altering the levels of certain chemicals in the brain that are involved in memory and other cognitive functions.

· Cholinesterase inhibitors (e.g. donepezil, galantamine, rivastigmine) increase the levels of acetylcholine, a neurotransmitter that is important for memory and thinking.

· NMDA receptor antagonists (e.g. memantine) work by blocking the NMDA receptors in the brain, reducing the excessive activity of neurons that is believed to contribute to the progression of Alzheimer's disease.

It's important to note that these medications do not cure the disease, but they may help improve symptoms and slow progression in some people.


How to use Alzheimer's medicines


Alzheimer's medications are usually taken orally, usually once or twice a day as prescribed by a doctor. It's important to follow the dosing instructions and schedule provided by your doctor, and to never adjust the dose or frequency of the medication without first consulting a doctor. It is also important to store medications safely and out of reach of children.

If you have questions or concerns about the use of Alzheimer's medication, please speak with your doctor or a pharmacist.


What are the side effects?


The side effects of Alzheimer's medications can vary depending on the specific drug, but some common side effects include:

· Nausea

· Diarrhea

· Vomiting

· Loss of appetite

· Weight loss

· Sleep disturbances

· Agitation or restlessness

· Dizziness

· Headaches

These side effects are usually mild and temporary, and may go away on their own over time. However, if you experience any severe or persistent side effects, or if you have any unusual symptoms, it is important to contact your doctor immediately.

In some cases, the side effects of Alzheimer's medication can be serious, and can even be life-threatening. For this reason, it is important to be aware of any potential side effects, and to talk to your doctor about any concerns you may have. Your doctor will be able to monitor your condition, and make any necessary adjustments to your medication regimen to minimize the risk of side effects.


When to discontinue Alzheimer's medicine?

Discontinuation of the medicine should only be done under the supervision of a healthcare professional. Factors that may lead to discontinuation include:


· Lack of effectiveness in improving symptoms

· Development of serious side effects

· Interactions with other medications

· Improvement of symptoms with alternative treatments

· Change in the patient's overall health or condition

It is important to regularly monitor the patient's response to the medication and to discuss any concerns with the healthcare provider to determine the best course of action.

What is Alzheimer?


The Alzheimer’s disease is a degenerative and progressive brain illness that make changes in thinking, memory, and behavior. It is the most common cause of dementia in older adults and can lead to a decline in cognitive abilities, including memory loss, difficulty with problem-solving and communication, and changes in mood and personality. The exact cause of this disease is not known, but a combination of genetic, environmental, and lifestyle factors are thought to play a role. There is currently no cure for the disease but medications and other treatments can help manage its symptoms.

How Alzheimer's medicines help to manage the disease?


The medicines help to manage the disease by treating symptoms like memory loss, confusion, and communication difficulties. These medicines work by changing the levels of certain chemicals in the brain or by blocking the breakdown of certain neurotransmitters. Some common types of Alzheimer's medications include cholinesterase inhibitors and NMDA receptor antagonists. They help to improve cognitive function, delay the progression of the disease, and improve quality of life for people with this disease. However, these medicines are not a cure for Alzheimer's and do not stop the underlying progression of the disease.


Can I use alcohol with Alzheimer's medicines?


It's not recommended to use alcohol while taking medicine for this disease, as it can interact with the medication and cause adverse effects. It can also increase the risk of falls, confusion, and other side effects. It's best to consult a doctor before drinking alcohol while taking any medication.

Does the medicine cure the Alzheimer completely?

No, there is currently no cure for Alzheimer's disease. Medications can help manage symptoms, slow progression, and improve quality of life for some people with Alzheimer's, but they do not cure the disease.

At what age does the disease affect?


The disease can affect people at any age, but it is most commonly diagnosed in people over 65 years old. Early-onset disease, which is rare, can occur in people as young as their 30s or 40s.

What things to be avoided while using Alzheimer's medicine?


When taking medications for dementia disease, it's important to avoid the following:


Over-the-counter pain relievers:

Avoid nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and naproxen, as these can increase the risk of bleeding in the brain.


Grapefruit juice:

This can interact with some Alzheimer's medications and increase the level of the drug in the bloodstream.


Alcohol:

Excessive alcohol can interact with Alzheimer's medications and cause adverse side effects.


Unnecessary medications:

Avoid taking unnecessary medications, especially sedatives and sleeping pills, as they can increase confusion and worsen memory loss.


Stopping medications abruptly:

If you need to stop or change your Alzheimer's medications, do so under the guidance of a healthcare professional to avoid adverse reactions.

It's also important to keep your healthcare provider informed of any changes in your health, symptoms, or medications to ensure safe and effective treatment for the disease.

Can Alzheimer's disease affect in young age?


Yes, although rare, early-onset dimentia disease can affect people in their 30s, 40s, and 50s. This type of dementia is also known as younger-onset Alzheimer's. It has similar symptoms to late-onset Alzheimer's but can have a more rapid progression and a greater impact on a person's life and abilities.

When to avoid Alzheimer's medicine?


There are some situations in which it may be necessary to temporarily stop or avoid taking these medications, such as:


When experiencing severe side effects:

If the medication is causing severe side effects, your doctor may recommend stopping it or switching to a different medication.

During a medical emergency:

If you are undergoing a medical procedure, such as surgery, your doctor may temporarily stop your Alzheimer's medication.

When interacting with other medications:

Some medications can interact with Alzheimer's drugs and cause harmful side effects. Your doctor may advise avoiding certain medications or adjusting the doses of your medications to minimize these interactions.

During pregnancy and breastfeeding:

The safety of Alzheimer's medications during pregnancy and breastfeeding is not well understood, and your doctor may advise avoiding these medications during these times.


It's important to never stop taking Alzheimer's medications without consulting with a healthcare professional, as abruptly discontinuing medication can cause adverse reactions and worsen symptoms.

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